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J Med Microbiol ; 69(5): 653-656, 2020 May.
Article in English | MEDLINE | ID: covidwho-108843

ABSTRACT

Much has happened here since the local news media trumpeted the first Australian COVID-19 fatality, and stirred up a medieval fear of contagion. We now need to take a step back to examine the logic underlying the use of our limited COVID-19 countermeasures. Emerging infectious diseases by their nature, pose new challenges to the diagnostic-treatment-control nexus, and push our concepts of causality beyond the limits of the conventional Koch-Henle approach to aetiology. We need to use contemporary methods of assessing causality to ensure that clinical, laboratory and public health measures draw on a rational, evidence-based approach to argumentation. The purpose of any aetiological hypothesis is to derive actionable insights into this latest emerging infectious disease. This review is an introduction to a conversation with medical microbiologists, which will be supported by a moderated blog.


Subject(s)
Betacoronavirus/pathogenicity , Communicable Diseases, Emerging/epidemiology , Containment of Biohazards/methods , Coronavirus Infections/epidemiology , Hygiene/education , Pneumonia, Viral/epidemiology , Amino Acid Substitution , Betacoronavirus/genetics , Betacoronavirus/growth & development , COVID-19 , Causality , China , Communicable Diseases, Emerging/diagnosis , Communicable Diseases, Emerging/immunology , Communicable Diseases, Emerging/therapy , Coronavirus Infections/diagnosis , Coronavirus Infections/immunology , Coronavirus Infections/therapy , Diagnostic Imaging/methods , Europe , Humans , Pandemics , Pneumonia, Viral/diagnosis , Pneumonia, Viral/immunology , Pneumonia, Viral/therapy , Public Health/trends , Reverse Transcriptase Polymerase Chain Reaction , SARS-CoV-2 , Viral Vaccines/biosynthesis , Viral Vaccines/immunology
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